Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810670 | 0.81 | ELANE (0.43) | GAAL3MBTL1BACE1ELANECTSG | |
| SCHEMBL18214383 | 0.78 | CYP3A4 (0.50) | GAAL3MBTL1BACE1ALDH1A1 | |
| SCHEMBL7789538 | 0.77 | GAA (0.47) | GAAL3MBTL1BACE1ATMELANE | |
| SCHEMBL22013858 | 0.77 | GAA (0.41) | GAAL3MBTL1ATMALDH1A1 | |
| SCHEMBL7997821 | 0.77 | GAA (0.41) | GAAL3MBTL1ATMALDH1A1 | |
| SCHEMBL9876467 | 0.71 | GAA (0.55) | GAAL3MBTL1BACE1ATMELANE | |
| SCHEMBL30953593 | 0.71 | MAOB (0.45) | ATMALDH1A1 | |
| SCHEMBL21961914 | 0.70 | POLB (0.42) | GAAL3MBTL1ALDH1A1 | |
| SCHEMBL22914872 | 0.70 | GAA (0.43) | GAAL3MBTL1BACE1ATM | |
| SCHEMBL19239808 | 0.70 | ELANE (0.40) | GAAL3MBTL1BACE1ELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403445-A1 | SYSTEMS AND METHODS FOR REGIOSELECTIVE CARBONYLATION OF 2,2-DISUBSTITUTED EPOXIDES | CORNELL UNIVERSITY | 2021-12-30 | — | — | US | disclosed |
| WO-2020102816-A1 | SYSTEMS AND METHODS FOR REGIOSELECTIVE CARBONYLATION OF 2,2-DISUBSTITUTED EPOXIDES | CORNELL UNIVERSITY (US) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403445-A1 | SYSTEMS AND METHODS FOR REGIOSELECTIVE CARBONYLATION OF 2,2-DISUBSTITUTED EPOXIDES | LTC4S, LSS, CYCS | GAA 2318/4885L3MBTL1 1369/4885BACE1 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.