SCHEMBL7359740

SCHEMBL7359740

CC(O[C]=O)c1cccc(N)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 1/20 0.39
CPB2 Q96IY4 1/20 0.39
CYP3A4 P08684 3/20 0.38
CASP1 P29466 1/20 0.38
RECQL P46063 1/20 0.38
ALDH1A1 P00352 1/20 0.37
MAPKAPK2 P49137 1/20 0.36
ADRB1 P08588 2/20 0.36
MIF P14174 1/20 0.36
HTR2A P28223 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR2B P41595 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
DDX3X O00571 1/20 0.34
TP53 P04637 1/20 0.34
ADRB2 P07550 5/20 0.34
ADRB3 P13945 1/20 0.34
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5539721 0.79 AOC3 (0.43) HTR2B
SCHEMBL5542650 0.79 CES2 (0.44)
SCHEMBL7749051 0.77 AOC3 (0.45)
SCHEMBL20852303 0.77 CYP3A4 (0.47) CPN1CPB2CYP3A4CASP1RECQL
SCHEMBL9157662 0.77 CYP3A4 (0.47) CPN1CPB2CYP3A4CASP1RECQL
SCHEMBL16970750 0.77 HCAR2 (0.43) ALDH1A1MIFADRA2AADRA2CLMNA
SCHEMBL16970628 0.77 HCAR2 (0.43) ALDH1A1MIFADRA2AADRA2CLMNA
SCHEMBL96935 0.77 HCAR2 (0.43) ALDH1A1MIFADRA2AADRA2CLMNA
SCHEMBL5544859 0.76 GLA (0.42) ADRA1A
SCHEMBL2865199 0.76 CYP3A4 (0.42) CPN1CPB2CYP3A4CASP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0846127-A1 ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY Novartis AG (CH) 1998-06-10 EP claimed
WO-1997008193-A1 ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY NOVARTIS AG (CH) 1997-03-06 WO claimed
EP-0846127-A1 ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY Novartis AG (CH) 1998-06-10 EP disclosed
WO-1997008193-A1 ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY NOVARTIS AG (CH) 1997-03-06 WO disclosed