Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.54 |
| ▸ | F2 | P00734 | 5/20 | 0.51 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.49 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.49 |
| ▸ | F12 | P00748 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CPN1 | P15169 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | C1S | P09871 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamidine SCHEMBL7366537 | 0.87 | F10 (0.67) | F10F2GABBR2GABBR1PRSS1 | |
| SCHEMBL7366288 | 0.85 | F10 (0.64) | F10F2PRSS1PRSS2PRSS3 | |
| 4-Methylbenzimidamide SCHEMBL7357637 | 0.83 | F10 (0.65) | F10F2PRSS1 | |
| SCHEMBL7456785 | 0.82 | F10 (0.71) | F10F2PRSS1 | |
| SCHEMBL2484805 | 0.81 | GABBR2 (0.66) | GABBR2GABBR1BLMFFAR1RECQL | |
| SCHEMBL240789 | 0.81 | GABBR2 (0.66) | GABBR2GABBR1BLMFFAR1RECQL | |
| SCHEMBL6174106 | 0.81 | GABBR2 (0.66) | GABBR2GABBR1BLMFFAR1RECQL | |
| SCHEMBL28628025 | 0.80 | FFAR1 (0.59) | GABBR2GABBR1BLMFFAR1KMT2A | |
| Methyl Benzoate SCHEMBL7359033 | 0.79 | F10 (0.61) | F10F2PRSS1 | |
| Benzamidine SCHEMBL27697030 | 0.77 | F2 (0.67) | F10F2F12F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |