Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.67 |
| ▸ | F2 | P00734 | 15/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.54 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.45 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methylbenzimidamide SCHEMBL7357637 | 0.92 | F10 (0.65) | F10F2PRSS1 | |
| SCHEMBL7456785 | 0.91 | F10 (0.71) | F10F2PRSS1 | |
| SCHEMBL7366288 | 0.91 | F10 (0.64) | F10F2PRSS1 | |
| Methyl Benzoate SCHEMBL7359033 | 0.90 | F10 (0.61) | F10F2PRSS1 | |
| Benzamide SCHEMBL7364697 | 0.88 | F10 (0.55) | F10F2PRSS1 | |
| Benzamidine SCHEMBL7359774 | 0.87 | F10 (0.54) | F10F2PRSS1GABBR2GABBR1 | |
| SCHEMBL7363610 | 0.86 | F10 (0.60) | F10F2PRSS1 | |
| Methyl Benzoate SCHEMBL7560351 | 0.84 | F2 (0.55) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL8346838 | 0.82 | F10 (0.53) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7463474 | 0.81 | F2 (0.54) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | claimed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | claimed |
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |