SCHEMBL736006

SCHEMBL736006

O=Cc1ncccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29572964 1.00
Acetic Acid SCHEMBL29148543 0.89 TRIM24 (0.43)
SCHEMBL28337559 0.82 TRIM24 (0.44)
SCHEMBL28335128 0.81 TRIM24 (0.43)
SCHEMBL25404021 0.77
SCHEMBL4609141 0.77
SCHEMBL8512088 0.76 S100A4 (0.45)
SCHEMBL346904 0.74 TRIM24 (0.59)
SCHEMBL890949 0.74 S100A4 (0.43)
SCHEMBL28338437 0.73 TRIM24 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613330-A 3-Bromopyridine derivative, continuous synthesis method and application thereof 苏州汉德创宏生化科技有限公司 2025-03-14 CN claimed
CN-113563280-B Synthesis method of 2-cyano phenothiazine 镇江卡博医药科技有限公司 2024-03-08 CN claimed
US-20260103454-A1 MODULATORS OF HEMOGLOBIN GLOBAL BLOOD THERAPEUTICS INC (US) 2026-04-16 US disclosed
EP-4724543-A1 IRIDIUM COMPLEXES USED AS PHOTOSENSITIZERS Université Grenoble Alpes (FR) 2026-04-15 EP disclosed
EP-4702017-A1 SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2026-03-04 EP disclosed
US-20260008767-A1 SOMATOSTATIN MODULATORS AND USES THEREOF CRINETICS PHARMACEUTICALS INC (US) 2026-01-08 US disclosed
EP-4665729-A1 DDR1 AND DDR2 INHIBITORS HAVING A DIHYDROBENZIMIDAZOLONE CORE Redx Pharma Limited (GB) 2025-12-24 EP disclosed
US-12435078-B2 Pyridazinones and methods of use thereof GFB (ABC), LLC (US) 2025-10-07 US disclosed
EP-4616906-A2 BENZO[A]PHENANTHRIDINE DERIVATIVES AS YAP/TAZ INHIBITORS Sanford Burnham Prebys Medical Discovery Institute (US) 2025-09-17 EP disclosed
EP-4612146-A1 AHR AGONISTS Eli Lilly and Company (US) 2025-09-10 EP disclosed
EP-4605392-A1 METHODS FOR TREATING CANCER Antares Therapeutics, Inc. (US) 2025-08-27 EP disclosed
EP-1270582-A1 TRIPHENYLPHOSPHINE DERIVATIVE, PRODUCTION PROCESS THEREFOR, PALLADIUM COMPLEX THEREOF, AND PROCESS FOR PRODUCING BIARYL DERIVATIVE Mitsubishi Rayon Co., Ltd. (JP) 2003-01-02 EP disclosed
WO-2002022600-A2 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS ANORMED INC. (CA) 2002-03-21 WO disclosed
US-6353110-B1 KEY INTERMEDIATE IN THE SYNTHESIS OF AN ENDOTHELIN ANTAGONIST; ARYLATION OF A 3-OXOPROPYLPYRIDINE WITH LITHIUM 1,3 BENZENEDIOXOLE THEN HYDROLYSIS MERCK & CO., INC. 2002-03-05 US disclosed
US-6022972-A Pyridine propanoic acid derivatives MERCK & CO., INC. (US) 2000-02-08 US disclosed
EP-0923557-A4 STEREOSELECTIVE DEOXYGENATION REACTION MERCK & CO INC (US) 1999-12-08 EP disclosed
US-5962688-A Stereoselective deoxygenation reaction MERCK & CO., INC. (US) 1999-10-05 US disclosed
EP-0923557-A1 STEREOSELECTIVE DEOXYGENATION REACTION Merck & Co., Inc. (US) 1999-06-23 EP disclosed
WO-1999007367-A1 ASYMMETRIC CONJUGATE ADDITION REACTION MERCK & CO., INC. (US) 1999-02-18 WO disclosed
WO-1998006700-A1 STEREOSELECTIVE DEOXYGENATION REACTION MERCK & CO., INC. (US) 1998-02-19 WO disclosed