SCHEMBL890949

SCHEMBL890949

O=Cc1ncccc1-c1cccnc1C=O.O=Cc1ncccc1-c1cccnc1C=O.O=Cc1ncccc1-c1cccnc1C=O.[Ru]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 3/20 0.43
CDC25B P30305 3/20 0.43
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
KMT2A Q03164 3/20 0.43
TDP2 O95551 2/20 0.43
NSD2 O96028 2/20 0.43
PAX8 Q06710 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 2/20 0.43
ABL1 P00519 1/20 0.43
PLCG1 P19174 1/20 0.43
CES1 P23141 1/20 0.43
RIN1 Q13671 1/20 0.43
THRB P10828 1/20 0.43
BLM P54132 1/20 0.43
GAA P10253 1/20 0.43
ALDH1A1 P00352 1/20 0.39
PTPRC P08575 2/20 0.39
CTSL P07711 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8512088 0.98 S100A4 (0.45) S100A4CDC25BTRIM24TRIM33KMT2A
SCHEMBL20578689 0.86 S100A4 (0.41) S100A4CDC25BTRIM24TRIM33KMT2A
SCHEMBL28337559 0.84 TRIM24 (0.44) S100A4CDC25BTRIM24TRIM33KMT2A
SCHEMBL4035576 0.84 ALDH1A1 (0.41) S100A4CDC25BTRIM24TRIM33KMT2A
SCHEMBL4658762 0.84 S100A4 (0.36) S100A4CDC25BTRIM24TRIM33KMT2A
SCHEMBL10768091 0.84 NFE2L2 (0.46) S100A4CDC25BGAAALDH1A1PTPRC
SCHEMBL3341430 0.84 ALDH1A1 (0.41) S100A4CDC25BTRIM24TRIM33KMT2A
SCHEMBL4129850 0.84 ALDH1A1 (0.48) S100A4CDC25BTRIM24TRIM33KMT2A
SCHEMBL2083077 0.83 ALDH1A1 (0.42) S100A4CDC25BTRIM24TRIM33KMT2A
SCHEMBL3342221 0.82 KDM4E (0.52) KMT2ATDP1MEN1BLMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210348215-A1 COMPOSITIONS, KITS AND METHODS FOR SYNTHESIS AND/OR DETECTION OF NUCLEIC ACIDS Life Technologies Corporation 2021-11-11 US disclosed
US-11091801-B2 Compositions, kits and methods for synthesis and/or detection of nucleic acids Life Technologies Corporation (US) 2021-08-17 US disclosed
EP-3502272-A1 COMPOSITIONS, KITS, AND METHODS FOR SYNTHESIS AND/OR DETECTION OF NUCLEIC ACIDS Life Technologies Corporation (US) 2019-06-26 EP disclosed
EP-3150723-B1 COMPOSITIONS, KITS, AND METHODS FOR SYNTHESIS AND/OR DETECTION OF NUCLEIC ACIDS LIFE TECHNOLOGIES CORP (US) 2019-01-30 EP disclosed
EP-3150723-A1 COMPOSITIONS, KITS, AND METHODS FOR SYNTHESIS AND/OR DETECTION OF NUCLEIC ACIDS Life Technologies Corporation (US) 2017-04-05 EP disclosed
US-20170002401-A1 COMPOSITIONS, KITS AND METHODS FOR SYNTHESIS AND/OR DETECTION OF NUCLEIC ACIDS Life Technologies Corporation 2017-01-05 US disclosed
EP-2582850-B1 COMPOSITIONS, KITS, AND METHODS FOR SYNTHESIS AND/OR DETECTION OF NUCLEIC ACIDS LIFE TECHNOLOGIES CORP (US) 2016-11-09 EP disclosed
US-9410194-B2 Compositions, kits and methods for synthesis and/or detection of nucleic acids Life Technologies Corporation (US) 2016-08-09 US disclosed
EP-1702216-B1 PHOSPHOR PARTICLE CODED BEADS LIFE TECHNOLOGIES CORP (US) 2015-11-04 EP disclosed
US-20140162258-A1 COMPOSITIONS, METHODS, AND KITS FOR (MIS)LIGATING OLIGONUCLEOTIDES APPLIED BIOSYSTEMS, LLC (US) 2014-06-12 US disclosed
US-20050260640-A1 Encoding and decoding reactions for determining target molecules APPLERA CORPORTION (US) 2005-11-24 US disclosed
WO-2005108618-A2 METHODS AND KITS FOR METHYLATION DETECTION APPLERA CORPORATION (US) 2005-11-17 WO disclosed
WO-2005098040-A2 LIGATION AND AMPLIFICATION REACTIONS FOR DETERMINING TARGET MOLECULES APPLERA CORPORATION (US) 2005-10-20 WO disclosed
WO-2005094532-A2 ENCODING AND DECODING REACTIONS FOR DETERMINING TARGET POLYNUCLEOTIDES APPLERA CORPORATION (US) 2005-10-13 WO disclosed
US-20050208543-A1 Phosphor particle coded beads APPLIED BIOSYSTEMS, LLC 2005-09-22 US disclosed
WO-2005071412-A2 PHOSPHOR PARTICLE CODED BEADS APPLERA CORPORATION (US) 2005-08-04 WO disclosed
US-20050074774-A1 Multiplex detection compositions, methods, and kits APPLERA CORPORATION (US) 2005-04-07 US disclosed
US-20050069895-A1 Compositions, methods, and kits for fabricating coded molecular tags APPLERA CORPORATION (US) 2005-03-31 US disclosed
WO-2005024021-A1 COMPOSITIONS, METHODS, AND KITS FOR ASSEMBLING PROBES COMPRISING CODED MOLECULAR TAGS APPLERA CORPORATION (US) 2005-03-17 WO disclosed
US-20050048498-A1 Compositions, methods, and kits for assembling probes APPLERA CORPORATION (US) 2005-03-03 US disclosed