Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27924561 | 0.84 | MGLL (0.52) | MGLLNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL27330799 | 0.82 | MGLL (0.50) | MGLLNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL2035775 | 0.78 | NPC1 (0.54) | MGLLNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL3786444 | 0.76 | NPC1 (0.68) | MGLLNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL3430834 | 0.74 | POLB (0.57) | MGLLNPC1RAB9APOLBSMN1; SMN2 | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.73 | POLB (0.78) | MGLLNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL3782118 | 0.73 | NPC1 (0.68) | MGLLNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL3795024 | 0.73 | POLB (0.68) | MGLLNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL30207803 | 0.73 | NPC1 (0.68) | MGLLNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL3791341 | 0.72 | MGLL (0.72) | MGLLNPC1RAB9AALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095022-A1 | RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002862-A1 | RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-01-20 | — | — | WO | disclosed |