Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790914 | 0.79 | BRD4 (0.34) | EPHX1EPHX2BRD4SMN1; SMN2LTA4H | |
| SCHEMBL8790490 | 0.77 | SMYD3 (0.48) | EPHX1EPHX2BRD4SMN1; SMN2SMYD3 | |
| SCHEMBL17282680 | 0.69 | BRD4 (0.44) | BRD4NR1H2 | |
| SCHEMBL22117717 | 0.68 | NR1H2 (0.52) | LTA4HNR1H2 | |
| SCHEMBL15360236 | 0.67 | BRD4 (0.49) | EPHX1BRD4SMN1; SMN2LTA4H | |
| SCHEMBL21652403 | 0.66 | BRD4 (0.41) | EPHX1BRD4NR1H2 | |
| SCHEMBL2864044 | 0.65 | BRD4 (0.50) | BRD4SMN1; SMN2LTA4H | |
| SCHEMBL12669611 | 0.64 | BRD4 (0.42) | EPHX1EPHX2BRD4SMN1; SMN2LTA4H | |
| SCHEMBL18096401 | 0.64 | MEN1 (0.34) | EPHX2NR1H2 | |
| SCHEMBL13713534 | 0.64 | EPHX2 (0.47) | EPHX1EPHX2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020172-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1996-07-04 | — | — | WO | disclosed |