Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13713534 | 0.86 | EPHX2 (0.47) | ALDH1A1EPHX1EPHX2GLANPC1 | |
| SCHEMBL7360344 | 0.83 | ITGB3 (0.44) | ALDH1A1EPHX1EPHX2GLANPC1 | |
| SCHEMBL12669611 | 0.80 | BRD4 (0.42) | ALDH1A1EPHX1EPHX2BRD4ITGB3 | |
| SCHEMBL8791486 | 0.80 | SMYD3 (0.52) | SMYD3NPC1ITGB3ITGA2B | |
| SCHEMBL23136277 | 0.78 | BRD4 (0.44) | EPHX1EPHX2BRD4 | |
| SCHEMBL2210266 | 0.78 | BRD4 (0.44) | ALDH1A1EPHX1EPHX2BRD4SMN1; SMN2 | |
| SCHEMBL11981636 | 0.78 | NPC1 (0.47) | SMYD3ALDH1A1EPHX1EPHX2NPC1 | |
| SCHEMBL13712962 | 0.78 | FAAH (0.43) | ALDH1A1EPHX1EPHX2GLABCHE | |
| SCHEMBL14147153 | 0.78 | SMYD3 (0.49) | SMYD3ALDH1A1NPC1ITGB3ITGA2B | |
| SCHEMBL7360348 | 0.77 | EPHX1 (0.34) | SMYD3EPHX1EPHX2BRD4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |