Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.31 |
| ▸ | FAP | Q12884 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791960 | 0.85 | ITGB3 (0.36) | DPP4FAPDPP7PREPDPP8 | |
| SCHEMBL8791967 | 0.85 | ITGB3 (0.36) | DPP4FAPDPP7PREPDPP8 | |
| SCHEMBL8790127 | 0.80 | CYP2C19 (0.41) | SMN1; SMN2DPP4DPP7PREP | |
| SCHEMBL8790582 | 0.80 | CYP2C19 (0.41) | SMN1; SMN2DPP4DPP7PREP | |
| SCHEMBL7360348 | 0.79 | EPHX1 (0.34) | BRD4SMN1; SMN2LTA4HEPHX1EPHX2 | |
| SCHEMBL19502859 | 0.74 | DPP4 (0.37) | DPP4FAPDPP7PREPDPP8 | |
| SCHEMBL17282680 | 0.69 | BRD4 (0.44) | BRD4NR1H2 | |
| SCHEMBL10232806 | 0.67 | BRD4 (0.42) | BRD4LTA4H | |
| SCHEMBL15360236 | 0.67 | BRD4 (0.49) | BRD4SMN1; SMN2LTA4HEPHX1 | |
| SCHEMBL21652403 | 0.66 | BRD4 (0.41) | BRD4EPHX1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |