Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | CHKA | P35790 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24620298 | 0.91 | MAPT (0.47) | CHRM5CHKASLC6A2MAPTCRHBP | |
| SCHEMBL27877152 | 0.80 | POLB (0.53) | MAPTCRHBPCRHR2MEN1NPC1 | |
| SCHEMBL49134 | 0.79 | CHRM5 (0.52) | CHRM5CHKASLC6A2MAPTSMN1; SMN2 | |
| SCHEMBL1036118 | 0.77 | CHRM5 (0.56) | CHRM5CHKASLC6A2MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7861604 | 0.77 | ALDH1A1 (0.50) | CHRM5CHKASLC6A2MAPTSMN1; SMN2 | |
| SCHEMBL3416208 | 0.74 | CHRM5 (0.58) | CHRM5CHKASLC6A2MAPTSMN1; SMN2 | |
| SCHEMBL11096837 | 0.73 | CHRM5 (0.73) | CHRM5CHKASLC6A2MAPTSMN1; SMN2 | |
| SCHEMBL409370 | 0.72 | NR3C2 (0.57) | SLC6A2MAPTCRHBPCRHR2NPSR1 | |
| Methyl Alcohol SCHEMBL28737572 | 0.72 | CHRM5 (0.57) | CHRM5CHKASLC6A2MAPTSMN1; SMN2 | |
| SCHEMBL6567347 | 0.72 | NR3C2 (0.57) | SLC6A2MAPTCRHBPCRHR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037343-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-03-14 | — | — | US | disclosed |
| EP-0796098-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0796098-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996019223-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-27 | — | — | WO | disclosed |