Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.47 |
| ▸ | STS | P08842 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.41 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360121 | 0.91 | PDE4B (0.48) | PDE4BSTSALDH1A1EPHX2MEN1 | |
| SCHEMBL7477254 | 0.88 | PDE4B (0.51) | PDE4BSTSALDH1A1EPHX2MEN1 | |
| SCHEMBL30606457 | 0.85 | GPR119 (0.53) | PDE4BSTSALDH1A1EPHX2MEN1 | |
| SCHEMBL7358039 | 0.85 | GPR119 (0.53) | PDE4BSTSALDH1A1EPHX2MEN1 | |
| SCHEMBL7475681 | 0.84 | PDE4B (0.52) | PDE4BSTSALDH1A1EPHX2PIK3CD | |
| SCHEMBL7403357 | 0.83 | PDE4B (0.47) | PDE4BSTSALDH1A1PDE4APDE4C | |
| SCHEMBL3151620 | 0.79 | STS (0.55) | PDE4BSTSALDH1A1EPHX2MEN1 | |
| SCHEMBL13407853 | 0.79 | GPR119 (0.44) | PDE4BSTSALDH1A1GPR119 | |
| SCHEMBL7472533 | 0.79 | PARP15 (0.52) | STSALDH1A1EPHX2GPR119 | |
| SCHEMBL7402370 | 0.78 | PDE4B (0.52) | PDE4BSTSALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805681-A4 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0805681-A1 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022775-A1 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-08-01 | — | — | WO | disclosed |