Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371160 | 0.94 | REN (0.64) | REN | |
| SCHEMBL11037229 | 0.92 | REN (0.67) | REN | |
| SCHEMBL9716892 | 0.92 | REN (0.65) | REN | |
| SCHEMBL8896012 | 0.91 | REN (0.62) | REN | |
| SCHEMBL8894149 | 0.91 | REN (0.62) | REN | |
| SCHEMBL10630607 | 0.90 | REN (0.67) | REN | |
| SCHEMBL10869206 | 0.90 | REN (0.59) | REN | |
| SCHEMBL10725721 | 0.90 | REN (0.59) | REN | |
| SCHEMBL10725717 | 0.90 | REN (0.59) | REN | |
| SCHEMBL9716785 | 0.89 | REN (0.69) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212903-B1 | POLYPEPTIDE DERIVATIVES CONTAINING 5-AMINO-2,5-DISUBSTITUTED-4-HYDROXYPENTANOIC ACID RESIDUES | PFIZER INC. (US) | 1992-12-30 | — | — | EP | disclosed |
| EP-0498361-A2 | Combination of an angiotensin II antagonist or renin inhibitor with a neutral endopeptidase inhibitor | SCHERING CORPORATION (US) | 1992-08-12 | — | — | EP | disclosed |
| EP-0270234-A2 | Renin inhibitors | PFIZER INC. (US) | 1988-06-08 | — | — | EP | disclosed |
| WO-1988003022-A1 | RELATIVELY LOW MOLECULAR WEIGHT POLYPEPTIDES AS RENIN INHIBITORS | PFIZER INC. (US) | 1988-05-05 | — | — | WO | disclosed |