Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360546 | 0.92 | REN (0.72) | REN | |
| SCHEMBL10630585 | 0.92 | REN (0.63) | REN | |
| SCHEMBL9716847 | 0.91 | REN (0.66) | REN | |
| SCHEMBL11018761 | 0.89 | REN (0.67) | REN | |
| SCHEMBL11023662 | 0.87 | REN (0.65) | REN | |
| SCHEMBL11014099 | 0.86 | REN (0.58) | REN | |
| SCHEMBL7371160 | 0.86 | REN (0.64) | REN | |
| SCHEMBL9502466 | 0.85 | REN (0.52) | REN | |
| SCHEMBL9504019 | 0.85 | REN (0.52) | REN | |
| SCHEMBL11037229 | 0.85 | REN (0.67) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077028-B1 | RENIN INHIBITORY PEPTIDES | MERCK & CO. INC. (US) | 1987-01-14 | — | — | EP | claimed |
| EP-0077028-A2 | Renin inhibitory peptides | MERCK & CO. INC. (US) | 1983-04-20 | — | — | EP | claimed |
| EP-0498361-A2 | Combination of an angiotensin II antagonist or renin inhibitor with a neutral endopeptidase inhibitor | SCHERING CORPORATION (US) | 1992-08-12 | — | — | EP | disclosed |