Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359427 | 0.88 | GPR119 (0.60) | GPR119MMP13F10PLGPRSS1 | |
| SCHEMBL24721250 | 0.82 | ALDH1A1 (0.65) | GPR119CHEK2NPC1ALDH1A1MAPT | |
| SCHEMBL7364906 | 0.81 | GPR119 (0.59) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL13423015 | 0.80 | GPR119 (0.60) | GPR119CHEK2NPC1ALDH1A1MAPT | |
| SCHEMBL23373231 | 0.79 | GPR119 (0.63) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8211504 | 0.79 | GPR119 (0.55) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5268593 | 0.79 | GPR119 (0.65) | GPR119CHEK2ALDH1A1USP30 | |
| SCHEMBL1649132 | 0.78 | GPR119 (0.64) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1375168 | 0.78 | GPR119 (0.61) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2735422 | 0.78 | GPR119 (0.67) | GPR119CHEK2ALDH1A1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805681-A4 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0805681-A1 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022775-A1 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-08-01 | — | — | WO | disclosed |