Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.61 |
| ▸ | DPP4 | P27487 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.54 |
| ▸ | FAP | Q12884 | 1/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161830 | 0.87 | OPRD1 (0.65) | OPRD1HDAC8DPP4OPRK1POLB | |
| SCHEMBL3133533 | 0.87 | OPRD1 (0.65) | OPRD1HDAC8DPP4OPRK1POLB | |
| SCHEMBL1337304 | 0.86 | HPGD (0.56) | HPGDOPRD1OPRK1GAADPP7 | |
| Hydrochloric Acid SCHEMBL6163295 | 0.86 | HDAC8 (0.63) | OPRD1HDAC8DPP4OPRK1POLB | |
| Hydrochloric Acid SCHEMBL6163301 | 0.86 | HDAC8 (0.63) | OPRD1HDAC8DPP4OPRK1POLB | |
| Hydrochloric Acid SCHEMBL6165745 | 0.86 | HDAC8 (0.63) | OPRD1HDAC8DPP4OPRK1POLB | |
| SCHEMBL5891540 | 0.85 | HDAC8 (0.60) | OPRD1HDAC8DPP4OPRK1POLB | |
| SCHEMBL6164884 | 0.85 | OPRD1 (0.60) | OPRD1HDAC8DPP4OPRK1POLB | |
| SCHEMBL2374566 | 0.85 | OPRD1 (0.69) | OPRD1HDAC8DPP4OPRK1POLB | |
| SCHEMBL2374558 | 0.85 | OPRD1 (0.69) | OPRD1HDAC8DPP4OPRK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |