Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361146 | 0.93 | F2 (0.40) | F2PRSS1PRSS2PRSS3CA1 | |
| Hydrochloric Acid SCHEMBL7361555 | 0.92 | F2 (0.39) | F2PRSS1PRSS2PRSS3CA1 | |
| Hydrochloric Acid SCHEMBL7463042 | 0.88 | F2 (0.38) | F2PRSS1PRSS2PRSS3CA1 | |
| Trifluoroacetic Acid SCHEMBL7458550 | 0.82 | F2 (0.41) | F2PRSS1PRSS2PRSS3RORC | |
| SCHEMBL7360778 | 0.78 | SMN1; SMN2 (0.41) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7363938 | 0.77 | LPAR1 (0.32) | CA1CA2ALDH1A1 | |
| SCHEMBL7364865 | 0.76 | SMN1; SMN2 (0.39) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7368094 | 0.74 | CA1 (0.38) | CA1CA2ALDH1A1CA9CA7 | |
| SCHEMBL7363751 | 0.72 | F2 (0.42) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7368633 | 0.71 | NR1H4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |