Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1625685 | 0.86 | MAPT (0.49) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL2129946 | 0.86 | ALDH1A1 (0.61) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL28113289 | 0.84 | MAPT (0.50) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL10783255 | 0.84 | HSD17B10 (0.50) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL18982074 | 0.83 | MEN1 (0.49) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL11327505 | 0.82 | ALDH1A1 (0.49) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL22165300 | 0.81 | MEN1 (0.49) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL11532393 | 0.79 | MAPT (0.57) | MAPTALDH1A1GAAHTTPOLB | |
| SCHEMBL1744734 | 0.78 | KDM4E (0.43) | MAPTALDH1A1GAAPOLBGLA | |
| SCHEMBL30001924 | 0.77 | HSD17B10 (0.56) | KMT2AALDH1A1TDP1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024405-A1 | IMIDAZOLIDIN-2-ONES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-09-14 | — | — | WO | disclosed |