Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360806 | 0.84 | KMT2A (0.49) | HSD17B10KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL10787003 | 0.83 | ALDH1A1 (0.51) | KMT2AMAPTALDH1A1CYP1A2TDP1 | |
| SCHEMBL2589891 | 0.81 | HSD17B10 (0.56) | HSD17B10KMT2ARAB9AALDH1A1CYP1A2 | |
| SCHEMBL30001924 | 0.81 | HSD17B10 (0.56) | HSD17B10KMT2ARAB9AALDH1A1CYP1A2 | |
| SCHEMBL7786691 | 0.79 | HSD17B10 (0.62) | HSD17B10KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL11303939 | 0.78 | HSD17B10 (0.53) | HSD17B10KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL4014324 | 0.78 | HSD17B10 (0.53) | HSD17B10KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL27897843 | 0.78 | KMT2A (0.59) | HSD17B10KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL23883005 | 0.78 | HSD17B10 (0.56) | HSD17B10KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL2595412 | 0.78 | HSD17B10 (0.56) | HSD17B10KMT2AALDH1A1CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659737-A | Substituted aminomethyl benzopyrans having anti-hypertensive activities | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |