Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 7/20 | 0.36 |
| ▸ | ANPEP | P15144 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591601 | 0.91 | CSNK1E (0.40) | CYP2C19CSNK1ESLC15A1EPHX1ALPI | |
| SCHEMBL6356875 | 0.72 | SLC15A1 (0.39) | CSNK1ESLC15A1EPHX1ALPIPKM | |
| SCHEMBL8059667 | 0.72 | SLC15A1 (0.39) | CSNK1ESLC15A1EPHX1ALPIPKM | |
| SCHEMBL27502071 | 0.71 | EPHX1 (0.52) | CSNK1ESLC15A1EPHX1ALPIPKM | |
| SCHEMBL6446370 | 0.68 | EPHX1 (0.58) | CSNK1ESLC15A1EPHX1ALPIPKM | |
| SCHEMBL6356479 | 0.68 | EPHX1 (0.58) | CSNK1ESLC15A1EPHX1ALPIPKM | |
| SCHEMBL6445044 | 0.68 | EPHX1 (0.58) | CSNK1ESLC15A1EPHX1ALPIPKM | |
| SCHEMBL6446300 | 0.68 | EPHX1 (0.58) | CSNK1ESLC15A1EPHX1ALPIPKM | |
| SCHEMBL22431194 | 0.68 | EPHX1 (0.58) | CSNK1ESLC15A1EPHX1ALPIPKM | |
| SCHEMBL9740410 | 0.68 | EPHX1 (0.58) | CSNK1ESLC15A1EPHX1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |