Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 7/20 | 0.38 |
| ▸ | ANPEP | P15144 | 4/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6356875 | 1.00 | SLC15A1 (0.39) | SLC15A1CSNK1ELAP3ANPEPEPHX1 | |
| SCHEMBL6356872 | 0.73 | LAP3 (0.41) | SLC15A1CSNK1ELAP3ANPEPEPHX1 | |
| SCHEMBL7360089 | 0.73 | LAP3 (0.41) | SLC15A1CSNK1ELAP3ANPEPEPHX1 | |
| SCHEMBL7361004 | 0.72 | CYP2C19 (0.43) | SLC15A1CSNK1ELAP3ANPEPEPHX1 | |
| SCHEMBL6349525 | 0.72 | TRPM8 (0.49) | — | |
| SCHEMBL6347819 | 0.71 | CSNK1E (0.41) | SLC15A1CSNK1ELAP3ANPEPEPHX1 | |
| SCHEMBL27502071 | 0.70 | EPHX1 (0.52) | SLC15A1CSNK1ELAP3ANPEPEPHX1 | |
| SCHEMBL10591601 | 0.70 | CSNK1E (0.40) | SLC15A1CSNK1ELAP3ANPEPEPHX1 | |
| SCHEMBL6356479 | 0.67 | EPHX1 (0.58) | SLC15A1CSNK1ELAP3ANPEPEPHX1 | |
| SCHEMBL6929688 | 0.67 | EPHX1 (0.58) | SLC15A1CSNK1ELAP3ANPEPEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1088706-C | Novel heterocyclic amide compound and medical use thereof | MAMORUFUKU KK (JP) | 2002-08-07 | — | — | CN | disclosed |
| US-6080738-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE USED FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II | YOSHITOMI PHARMACEUTICALS INDUSTRIES, LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| CN-1242014-A | Novel heterocyclic amide compounds and medicinal uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2000-01-19 | — | — | CN | disclosed |
| EP-0940400-A1 | NOVEL HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USES THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-08 | — | — | EP | disclosed |