Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ANPEP | P15144 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 3/20 | 0.41 |
| ▸ | GABRD | O14764 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823258 | 0.89 | ENPEP (0.74) | ENPEPALDH1A1ANPEPTSHRBLM | |
| SCHEMBL298510 | 0.84 | ENPEP (0.68) | ENPEPALDH1A1ANPEPTSHRBLM | |
| SCHEMBL11545521 | 0.84 | ALDH1A1 (0.73) | ENPEPALDH1A1ANPEPTSHRBLM | |
| SCHEMBL287856 | 0.84 | ENPEP (0.68) | ENPEPALDH1A1ANPEPTSHRBLM | |
| SCHEMBL336856 | 0.81 | ALDH1A1 (0.76) | ENPEPALDH1A1ANPEPTSHRBLM | |
| SCHEMBL27762577 | 0.79 | ALDH1A1 (0.80) | ENPEPALDH1A1ANPEPTSHRKMT2A | |
| SCHEMBL27705304 | 0.79 | ALDH1A1 (0.80) | ENPEPALDH1A1ANPEPTSHRKMT2A | |
| SCHEMBL29255900 | 0.79 | ALDH1A1 (0.80) | ENPEPALDH1A1ANPEPTSHRKMT2A | |
| SCHEMBL1878508 | 0.78 | ALDH1A1 (0.71) | ENPEPALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL466531 | 0.78 | ALDH1A1 (0.85) | ENPEPALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722321-A4 | SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1998-04-15 | — | — | EP | disclosed |
| EP-0722321-A1 | SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009620-A1 | SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |