Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 3/20 | 0.67 |
| ▸ | ANPEP | P15144 | 1/20 | 0.67 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.67 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.67 |
| ▸ | MMP8 | P22894 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7353077 | 0.99 | LAP3 (0.66) | LAP3ANPEPRNPEPDNPEPMMP8 | |
| SCHEMBL7950693 | 0.90 | LAP3 (0.72) | LAP3ANPEPRNPEPDNPEPMMP8 | |
| SCHEMBL8498476 | 0.86 | LAP3 (0.71) | LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL27916353 | 0.86 | LAP3 (0.71) | LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL8498473 | 0.86 | LAP3 (0.71) | LAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL27660947 | 0.85 | LAP3 (0.70) | LAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL4398341 | 0.85 | LAP3 (0.70) | LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL6873773 | 0.84 | LAP3 (0.62) | LAP3ANPEPRNPEPDNPEPKMT2A | |
| SCHEMBL6876417 | 0.83 | LAP3 (0.60) | LAP3ANPEPRNPEPDNPEPKMT2A | |
| SCHEMBL6873623 | 0.83 | LAP3 (0.60) | LAP3ANPEPRNPEPDNPEPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242494-B1 | ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES | 2001-06-05 | — | — | US | claimed |
| EP-1073633-A2 | SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 | ABBOTT LABORATORIES (US) | 2001-02-07 | — | — | EP | claimed |
| WO-1999057098-A2 | SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 | ABBOTT LABORATORIES (US) | 1999-11-11 | — | — | WO | claimed |
| US-6242494-B1 | ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES | 2001-06-05 | — | — | US | disclosed |
| EP-1073633-A2 | SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 | ABBOTT LABORATORIES (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999057098-A2 | SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 | ABBOTT LABORATORIES (US) | 1999-11-11 | — | — | WO | disclosed |