Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.72 |
| ▸ | ANPEP | P15144 | 1/20 | 0.72 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.72 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.72 |
| ▸ | METAP2 | P50579 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | METAP1 | P53582 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361190 | 0.90 | LAP3 (0.67) | LAP3ANPEPRNPEPDNPEPMETAP2 | |
| Hydrochloric Acid SCHEMBL7353077 | 0.89 | LAP3 (0.66) | LAP3ANPEPRNPEPDNPEPMETAP2 | |
| SCHEMBL3135806 | 0.87 | LAP3 (0.75) | LAP3ANPEPRNPEPDNPEPMETAP2 | |
| SCHEMBL14973840 | 0.87 | POLB (0.61) | LAP3ANPEPRNPEPDNPEPMETAP2 | |
| SCHEMBL10635162 | 0.85 | POLB (0.61) | KMT2APOLBMMP8CA12CA2 | |
| SCHEMBL9192833 | 0.85 | POLB (0.61) | KMT2APOLBMMP8CA12CA2 | |
| SCHEMBL7924570 | 0.85 | METAP2 (0.60) | LAP3ANPEPRNPEPDNPEPMETAP2 | |
| Hydrochloric Acid SCHEMBL4397404 | 0.85 | LAP3 (0.73) | LAP3ANPEPRNPEPDNPEPMETAP2 | |
| SCHEMBL17097365 | 0.84 | LAP3 (0.68) | LAP3ANPEPRNPEPDNPEPKMT2A | |
| SCHEMBL7951029 | 0.84 | LAP3 (0.68) | LAP3ANPEPRNPEPDNPEPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1169791-C | Novel acetamide derivatives and protease inhibitors | �ձ���ҩ��ʽ���� | 2004-10-06 | — | — | CN | disclosed |
| US-6271238-B1 | USEFUL IN TREATING AND PREVENTING DISEASES INVOLVING CHYMOTRYPSIN TYPE PROTEASES WHICH ARE RELATED TO ASTHMA, ALLERGY, INFLAMMATIONS, RHEUMATISM, HYPERTENSION, HEART FAILURE, MYOCARDIAL INFARCTION, AND CARDIAC HYPERTROPHY | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | disclosed |
| CN-1229405-A | Novel acetamide derivatives and protease inhibitors | NIPPON KAYAKU KK (JP) | 1999-09-22 | — | — | CN | disclosed |
| EP-0936216-A1 | NOVEL ACETAMIDE DERIVATIVES AND PROTEASE INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-08-18 | — | — | EP | disclosed |