Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.56 |
| ▸ | PDE4A | P27815 | 6/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373126 | 0.94 | ALDH1A1 (0.58) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL498305 | 0.92 | PDE4D (0.57) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL497697 | 0.92 | PDE4D (0.57) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL497696 | 0.92 | PDE4D (0.57) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL22713946 | 0.90 | ALDH1A1 (0.68) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL6883557 | 0.88 | ALDH1A1 (0.66) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL70835 | 0.87 | ALDH1A1 (0.64) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL29808190 | 0.87 | ALDH1A1 (0.64) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL7560477 | 0.87 | ALDH1A1 (0.64) | ALDH1A1TSHRPDE4BPDE4DPDE4A | |
| SCHEMBL28376693 | 0.86 | PDE4D (0.57) | ALDH1A1TSHRPDE4BPDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981876-B | 8-substituted styrylxanthine derivatives and uses thereof | 广东东阳光药业有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-110981876-A | 8-substituted styrylxanthine derivatives and uses thereof | 广东东阳光药业有限公司 | 2020-04-10 | — | — | CN | disclosed |
| EP-0741707-B1 | SUBSTITUTED AROMATIC COMPOUNDS AS c.AMP PHOSPHODIESTERASE- AND TNF-INHIBITORS | RHONE POULENC RORER LTD (GB) | 1998-04-01 | — | — | EP | disclosed |
| EP-0741707-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS c.AMP PHOSPHODIESTERASE- AND TNF-INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020578-A1 | SUBSTITUTED AROMATIC COMPOUNDS AS c.AMP PHOSPHODIESTERASE- AND TNF-INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1995-08-03 | — | — | WO | disclosed |