Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402157 | 0.75 | CYP1A2 (0.46) | ALDH1A1CYP1A2LMNACYP2C9CYP2C19 | |
| SCHEMBL7361069 | 0.74 | CYP1A2 (0.45) | ALDH1A1CYP1A2LMNAMTNR1AMTNR1B | |
| SCHEMBL7365439 | 0.73 | HRH1 (0.43) | FFAR4PPARAALDH1A1KDM4E | |
| SCHEMBL7358486 | 0.72 | CYP1A2 (0.43) | ALDH1A1CYP1A2LMNACYP2C9CYP2C19 | |
| SCHEMBL7363747 | 0.72 | GRM2 (0.44) | ALDH1A1CYP1A2LMNAMTNR1AMTNR1B | |
| SCHEMBL7398125 | 0.71 | GRM2 (0.48) | ALDH1A1CYP1A2GRM2GRM3KMT2A | |
| SCHEMBL5053068 | 0.71 | CFTR (0.42) | ALDH1A1CYP1A2LMNACYP2C9CYP2C19 | |
| SCHEMBL5512521 | 0.70 | LMNA (0.57) | PPARGPPARAALDH1A1LMNAMTNR1A | |
| SCHEMBL10288771 | 0.70 | FFAR4 (0.74) | FFAR4 | |
| SCHEMBL10254312 | 0.70 | FFAR4 (0.74) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |