Saccharin

Saccharin

SCHEMBL7361433

O=S1(=O)N=C(O)c2ccccc21

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
KCNA3 P22001 2/20 0.50
PKM P14618 2/20 0.49
LMNA P02545 3/20 0.45
HSD17B10 Q99714 2/20 0.45
HTT P42858 2/20 0.45
GAA P10253 1/20 0.45
TSHR P16473 1/20 0.45
GPR3 P46089 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
HPGD P15428 1/20 0.44
EPAS1 Q99814 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9292620 0.74 ALDH1A1 (0.50) ALDH1A1KCNA3PKMLMNAHSD17B10
SCHEMBL652970 0.74 PKM (0.53) ALDH1A1KCNA3PKMLMNAHSD17B10
SCHEMBL8285711 0.74 ALDH1A1 (0.50) ALDH1A1KCNA3PKMLMNAHSD17B10
SCHEMBL299692 0.74 ALDH1A1 (0.50) ALDH1A1KCNA3PKMLMNAHSD17B10
SCHEMBL299421 0.74 ALDH1A1 (0.50) ALDH1A1KCNA3PKMLMNAHSD17B10
SCHEMBL29695488 0.74 ALDH1A1 (0.50) ALDH1A1KCNA3PKMLMNAHSD17B10
SCHEMBL28235819 0.74 ALDH1A1 (0.50) ALDH1A1KCNA3PKMLMNAHSD17B10
Saccharin SCHEMBL29383369 0.72 ALDH1A1 (0.49) ALDH1A1KCNA3PKMLMNAHSD17B10
Saccharin SCHEMBL29646270 0.72 ALDH1A1 (0.49) ALDH1A1KCNA3PKMLMNAHSD17B10
Saccharin SCHEMBL18741026 0.72 ALDH1A1 (0.49) ALDH1A1KCNA3PKMLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107827926-A Surfactant of Small Molecule Functionalization and its preparation method and application 中国科学院兰州化学物理研究所 2018-03-23 CN claimed
CN-106868571-A A kind of nanometer molybdenum palladium titanium electroplate liquid and preparation method thereof 句容亿格纳米材料厂 2017-06-20 CN claimed
CN-101456847-B Probenazole preparation method TIANJIN XINWEI CHEMICAL CO LTD 2010-08-11 CN claimed
CN-101456847-A Probenazole and preparation method thereof TIANJIN XINWEI CHEMICAL CO LTD (CN) 2009-06-17 CN claimed
CN-117529366-A Ion exchange membrane, method for producing ion exchange membrane, and ion exchange membrane unit 国立大学法人山口大学 2024-02-06 CN disclosed
CN-111406055-B Microbiocidal thiazole derivatives 先正达参股股份有限公司 2023-09-22 CN disclosed
CN-110382492-B Microbiocidal oxadiazole derivatives 先正达参股股份有限公司 2023-07-14 CN disclosed
CN-114938748-A Chemical weeding method for direct seeding beet field 张北县保丰种植专业合作社 2022-08-26 CN disclosed
CN-114555124-A Pharmaceutical co-crystal salt formulation 瑟拉诺沃控股有限公司 2022-05-27 CN disclosed
CN-107875168-B Application of immunoregulation composition in treating malignant hydrops 广州百吉生物制药有限公司 2022-03-04 CN disclosed
CN-113727703-A Carrier system for preparing herbal extracts SISAF有限公司 2021-11-30 CN disclosed
CN-113633634-A Formulations of2- (4-chlorophenyl) -N- ((2- (2,6-dioxopiperidin-3-yl) -1-oxoisoindolin-5-yl) methyl) -2,2-difluoroacetamide 细胞基因公司 2021-11-12 CN disclosed
WO-2013104877-A1 IMPROVEMENTS IN COATING TECHNOLOGY JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2013-07-18 WO disclosed
CN-101456847-B Probenazole preparation method TIANJIN XINWEI CHEMICAL CO LTD 2010-08-11 CN disclosed
CN-101456847-A Probenazole and preparation method thereof TIANJIN XINWEI CHEMICAL CO LTD (CN) 2009-06-17 CN disclosed
CN-100357322-C Disintegrating element for poisonous snake and its coding gene and use FIELD TRANSFUSION INST MILITAR (CN) 2007-12-26 CN disclosed
CN-1709909-A Disintegrating element for poisonous snake and its coding gene and use FIELD TRANSFUSION INST MILITAR (CN) 2005-12-21 CN disclosed
EP-1175419-A2 ARYL SULFONYLS AS FACTOR XA INHIBITORS Du Pont Pharmaceuticals Company (US) 2002-01-30 EP disclosed
WO-2000059902-A2 ARYL SULFONYLS AS FACTOR XA INHIBITORS DU PONT PHARMACEUTICALS COMPANY (US) 2000-10-12 WO disclosed
EP-0154274-A2 Process for the preparation of 3-hydrazino-1,2-benzisothiazole-1,1-dioxide BAYER AG (DE) 1985-09-11 EP disclosed