Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 8/20 | 0.42 |
| ▸ | MMP1 | P03956 | 14/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 11/20 | 0.40 |
| ▸ | MMP3 | P08254 | 5/20 | 0.40 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
| ▸ | MMP8 | P22894 | 4/20 | 0.40 |
| ▸ | MMP7 | P09237 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415490 | 0.87 | MMP1 (0.47) | FCER2MMP1ADAM17MMP2MMP3 | |
| SCHEMBL7365448 | 0.86 | MMP1 (0.55) | FCER2MMP1ADAM17MMP2MMP3 | |
| SCHEMBL8749878 | 0.82 | MMP1 (0.57) | FCER2MMP1ADAM17MMP2MMP3 | |
| SCHEMBL7356209 | 0.81 | MMP1 (0.49) | FCER2MMP1ADAM17MMP2MMP3 | |
| SCHEMBL6416122 | 0.81 | MMP1 (0.47) | FCER2MMP1ADAM17MMP2MMP3 | |
| SCHEMBL7358017 | 0.81 | MMP1 (0.61) | FCER2MMP1ADAM17MMP2MMP3 | |
| SCHEMBL7365016 | 0.81 | FCER2 (0.45) | FCER2MMP1ADAM17MMP2MMP3 | |
| SCHEMBL7361142 | 0.81 | FCER2 (0.46) | FCER2MMP1ADAM17MMP2MMP3 | |
| SCHEMBL7391172 | 0.80 | MMP1 (0.47) | FCER2MMP1ADAM17MMP2MMP3 | |
| SCHEMBL6412867 | 0.80 | MMP3 (0.51) | FCER2MMP1ADAM17MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691382-A | ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |
| EP-0667770-B1 | INHIBITION OF TNF PRODUCTION | BRITISH BIOTECH PHARM (GB) | 1997-03-19 | — | — | EP | disclosed |
| EP-0667770-A1 | INHIBITION OF TNF PRODUCTION. | BRITISH BIOTECH PHARM (GB) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010990-A1 | INHIBITION OF TNF PRODUCTION | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1994-05-26 | — | — | WO | disclosed |