SCHEMBL7361452

SCHEMBL7361452

CCCC(F)OC(=O)C=CCCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7363348 0.92 MAPT (0.42) GPR52
SCHEMBL1268421 0.76 MAPT (0.62) GPR52
SCHEMBL1268422 0.76 MAPT (0.62) GPR52
SCHEMBL5972763 0.75 GPR52 (0.60) GPR52
SCHEMBL7374431 0.75 GPR52 (0.60) GPR52
SCHEMBL27310628 0.73 MAPT (0.59) GPR52
SCHEMBL27310629 0.73 MAPT (0.59) GPR52
SCHEMBL27311625 0.73 MAPT (0.59) GPR52
SCHEMBL27311627 0.73 MAPT (0.59) GPR52
SCHEMBL6824553 0.72 GPR52 (0.55) GPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0871439-A4 SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS RHONE POULENC RORER PHARMA (US) 1999-07-21 EP disclosed
EP-0871439-A1 SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1998-10-21 EP disclosed
WO-1997024117-A1 SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1997-07-10 WO disclosed