Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.61 |
| ▸ | F2 | P00734 | 3/20 | 0.61 |
| ▸ | F7 | P08709 | 2/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.61 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.61 |
| ▸ | PLAU | P00749 | 2/20 | 0.61 |
| ▸ | PLG | P00747 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.60 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.60 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029320 | 0.91 | RAB9A (0.53) | F10F2F7PRSS1TPSAB1 | |
| SCHEMBL7366854 | 0.90 | F10 (0.55) | F10F2F7PRSS1TPSAB1 | |
| SCHEMBL8031089 | 0.90 | F10 (0.65) | F10F2F7PRSS1TPSAB1 | |
| SCHEMBL7361483 | 0.88 | F10 (0.57) | F10F2F7PRSS1TPSAB1 | |
| SCHEMBL7362340 | 0.85 | F10 (0.58) | F10F2F7PRSS1TPSAB1 | |
| SCHEMBL7367804 | 0.81 | F7 (0.46) | F10F2F7PRSS1TPSAB1 | |
| SCHEMBL7364435 | 0.81 | F10 (0.50) | F10F2F7PRSS1TPSAB1 | |
| SCHEMBL7365504 | 0.80 | F10 (0.47) | F10F2F7PRSS1TPSAB1 | |
| SCHEMBL7398843 | 0.80 | F10 (0.53) | F10F2F7PRSS1TPSAB1 | |
| SCHEMBL7441084 | 0.77 | F10 (0.55) | F10F2F7PRSS1TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0960102-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | Du Pont Pharmaceuticals Company (US) | 1999-12-01 | — | — | EP | disclosed |
| US-5886191-A | ANTICOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| WO-1998001428-A1 | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |