Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 6/20 | 0.48 |
| ▸ | FAP | Q12884 | 6/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362111 | 0.87 | ALDH1A1 (0.46) | PREPFAPALDH1A1DPP8DPP9 | |
| SCHEMBL7367822 | 0.86 | PREP (0.52) | PREPFAPDPP8DPP9LMNA | |
| SCHEMBL7366766 | 0.86 | PREP (0.66) | PREPFAPALDH1A1DPP8DPP9 | |
| SCHEMBL7361706 | 0.81 | ACE (0.45) | PREPFAPALDH1A1LMNAACE | |
| SCHEMBL7363975 | 0.80 | CYP2C19 (0.52) | PREPFAPALDH1A1DPP8DPP9 | |
| SCHEMBL7360180 | 0.80 | ALDH1A1 (0.44) | PREPFAPALDH1A1DPP8DPP9 | |
| SCHEMBL7367819 | 0.79 | ALDH1A1 (0.43) | PREPFAPALDH1A1DPP8DPP9 | |
| SCHEMBL8721003 | 0.78 | PREP (0.49) | PREPFAPALDH1A1DPP8DPP9 | |
| SCHEMBL7362731 | 0.77 | SMYD3 (0.50) | PREPFAPALDH1A1DPP8DPP9 | |
| SCHEMBL7362190 | 0.77 | ALDH1A1 (0.43) | PREPFAPALDH1A1DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500989-B1 | N-(alpha-substituted-pyridinyl) carbonyl dipeptide antihypertensive agents | LACER SA (ES) | 1998-12-09 | — | — | EP | disclosed |
| US-5432159-A | N-(α-substituted-pyridinyl)carbonyl dipeptide antihypertensive agents | LACER S.A. (ES) | 1995-07-11 | — | — | US | disclosed |
| WO-1992015608-A1 | N-(α-SUBSTITUTED-PYRIDINYL)CARBONYL DIPEPTIDE ANTIHYPERTENSIVE AGENTS | LACER S.A. (ES) | 1992-09-17 | — | — | WO | disclosed |
| EP-0500989-A1 | N-(alpha-substituted-pyridinyl) carbonyl dipeptide antihypertensive agents | LACER, S.A. (ES) | 1992-09-02 | — | — | EP | disclosed |