Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 10/20 | 0.66 |
| ▸ | FAP | Q12884 | 7/20 | 0.66 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721003 | 0.86 | PREP (0.49) | PREPFAPDPP8DPP9ALDH1A1 | |
| SCHEMBL7358412 | 0.86 | PREP (0.73) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL7361568 | 0.86 | PREP (0.48) | PREPFAPDPP8DPP9ALDH1A1 | |
| SCHEMBL7363975 | 0.81 | CYP2C19 (0.52) | PREPFAPDPP8DPP9ALDH1A1 | |
| SCHEMBL7361706 | 0.80 | ACE (0.45) | PREPFAPALDH1A1ACELMNA | |
| SCHEMBL7362190 | 0.80 | ALDH1A1 (0.43) | PREPFAPDPP8DPP9ALDH1A1 | |
| SCHEMBL7362731 | 0.80 | SMYD3 (0.50) | PREPFAPDPP8DPP9ALDH1A1 | |
| SCHEMBL7362111 | 0.79 | ALDH1A1 (0.46) | PREPFAPDPP8DPP9ALDH1A1 | |
| SCHEMBL7360180 | 0.77 | ALDH1A1 (0.44) | PREPFAPDPP8DPP9ALDH1A1 | |
| SCHEMBL17345172 | 0.77 | PREP (0.58) | PREPFAPDPP8DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500989-B1 | N-(alpha-substituted-pyridinyl) carbonyl dipeptide antihypertensive agents | LACER SA (ES) | 1998-12-09 | — | — | EP | disclosed |
| US-5432159-A | N-(α-substituted-pyridinyl)carbonyl dipeptide antihypertensive agents | LACER S.A. (ES) | 1995-07-11 | — | — | US | disclosed |
| WO-1992015608-A1 | N-(α-SUBSTITUTED-PYRIDINYL)CARBONYL DIPEPTIDE ANTIHYPERTENSIVE AGENTS | LACER S.A. (ES) | 1992-09-17 | — | — | WO | disclosed |
| EP-0500989-A1 | N-(alpha-substituted-pyridinyl) carbonyl dipeptide antihypertensive agents | LACER, S.A. (ES) | 1992-09-02 | — | — | EP | disclosed |