Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360990 | 0.88 | MEN1 (0.39) | LMNA | |
| SCHEMBL7361163 | 0.82 | PPARA (0.54) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7360752 | 0.80 | PPARA (0.49) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7364879 | 0.80 | PPARA (0.47) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7366901 | 0.79 | MCHR1 (0.39) | LMNA | |
| SCHEMBL7367480 | 0.79 | PPARA (0.47) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7362850 | 0.77 | PPARA (0.44) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7360754 | 0.77 | PPARA (0.49) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL7368682 | 0.73 | TSHR (0.45) | LMNASMN1; SMN2 | |
| SCHEMBL7367034 | 0.73 | PPARA (0.44) | PPARAPPARGPPARDPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |