Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360990 | 0.92 | MEN1 (0.39) | MCHR1APEX1MAPK10ROCK2ROCK1 | |
| SCHEMBL7370696 | 0.88 | LMNA (0.45) | MCHR1APEX1LMNAPDE5AHPGD | |
| SCHEMBL7371272 | 0.83 | PDE5A (0.47) | LMNAPDE5AHPGD | |
| SCHEMBL7366361 | 0.81 | LMNA (0.44) | APEX1ROCK2ROCK1LMNAHPGD | |
| SCHEMBL7361602 | 0.79 | PPARA (0.48) | LMNA | |
| SCHEMBL7368682 | 0.79 | TSHR (0.45) | APEX1MAPK10LMNAALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7361883 | 0.78 | TSHR (0.45) | APEX1MAPK10LMNAALDH1A1TSHR | |
| SCHEMBL7390175 | 0.77 | APEX1 (0.47) | APEX1MAPK10LMNAALDH1A1TSHR | |
| SCHEMBL7364564 | 0.76 | APEX1 (0.42) | APEX1MAPK10LMNAALDH1A1TSHR | |
| SCHEMBL7391615 | 0.74 | APEX1 (0.46) | APEX1MAPK10LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |