Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361604 | 1.00 | ADORA2B (0.38) | ADORA2BKDM4EHSD17B10HPGDPKM | |
| SCHEMBL7321057 | 1.00 | ADORA2B (0.38) | ADORA2BKDM4EHSD17B10HPGDPKM | |
| SCHEMBL7269604 | 0.78 | ADORA2B (0.40) | ADORA2BKDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7269607 | 0.78 | ADORA2B (0.40) | ADORA2BKDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7285419 | 0.78 | ADORA2B (0.40) | ADORA2BKDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7300104 | 0.78 | ADORA2B (0.40) | ADORA2BKDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL7278836 | 0.77 | POLB (0.36) | HTTMEN1KMT2A | |
| SCHEMBL7278830 | 0.77 | POLB (0.36) | HTTMEN1KMT2A | |
| SCHEMBL7319306 | 0.74 | KDM4E (0.39) | ADORA2BKDM4EHSD17B10HPGDPKM | |
| SCHEMBL7319314 | 0.74 | KDM4E (0.39) | ADORA2BKDM4EHSD17B10HPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189023-A | Hypotensive agent | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0473936-A1 | Renin Inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |