Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248305 | 0.90 | CTSB (0.55) | CTSBSMN1; SMN2CTRC | |
| SCHEMBL20204722 | 0.89 | CTSB (0.62) | CTSBSMN1; SMN2CAPN1 | |
| SCHEMBL23234581 | 0.86 | CTSB (0.58) | CTSBSMN1; SMN2CAPN1CTRC | |
| SCHEMBL622495 | 0.86 | CTSB (0.58) | CTSBSMN1; SMN2CAPN1 | |
| SCHEMBL7358373 | 0.85 | CTSB (0.44) | CTSBSMN1; SMN2CTRCCTRB1 | |
| SCHEMBL7358371 | 0.85 | CTSB (0.44) | CTSBSMN1; SMN2CTRCCTRB1 | |
| SCHEMBL9001090 | 0.85 | CTSB (0.55) | CTSBSMN1; SMN2CAPN1 | |
| SCHEMBL23234613 | 0.85 | CTSB (0.57) | CTSBSMN1; SMN2CAPN1 | |
| SCHEMBL2269431 | 0.84 | CAPN1 (0.58) | CTSBCAPN1CTRB1 | |
| SCHEMBL5563236 | 0.84 | CAPN1 (0.58) | CTSBCAPN1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |