Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
| ▸ | PGC | P20142 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358373 | 1.00 | CTSB (0.44) | CTSBSMN1; SMN2CTRCCTSDCTSE | |
| SCHEMBL7361635 | 0.85 | CTSB (0.59) | CTSBSMN1; SMN2CTRCCTRB1 | |
| SCHEMBL29112224 | 0.78 | MME (0.58) | — | |
| SCHEMBL7270319 | 0.77 | CTSS (0.52) | CTSDCTSEPGCCTRB1 | |
| SCHEMBL7279589 | 0.76 | CA2 (0.56) | CTSDCTSEPGC | |
| SCHEMBL7362372 | 0.76 | CYP3A4 (0.66) | CTSDCTSEPGCCTRB1LMNA | |
| SCHEMBL6248305 | 0.76 | CTSB (0.55) | CTSBSMN1; SMN2CTRCCTSD | |
| SCHEMBL7358377 | 0.75 | CTSB (0.39) | CTSBCTRB1 | |
| SCHEMBL20204722 | 0.75 | CTSB (0.62) | CTSBSMN1; SMN2 | |
| SCHEMBL7364425 | 0.73 | CTSD (0.56) | CTSDCTSEPGC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |