Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | VCP | P55072 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361664 | 1.00 | NFE2L2 (0.60) | NFE2L2CYP19A1FBP1VCPRAB9A | |
| SCHEMBL6798527 | 0.83 | NFE2L2 (0.60) | NFE2L2CYP19A1FBP1VCPRAB9A | |
| SCHEMBL6798522 | 0.83 | NFE2L2 (0.60) | NFE2L2CYP19A1FBP1VCPRAB9A | |
| SCHEMBL6797337 | 0.82 | NFE2L2 (0.68) | NFE2L2CYP19A1FBP1VCPRAB9A | |
| SCHEMBL6797334 | 0.82 | NFE2L2 (0.68) | NFE2L2CYP19A1FBP1VCPRAB9A | |
| SCHEMBL15498134 | 0.81 | NFE2L2 (0.89) | NFE2L2CYP19A1FBP1VCPRAB9A | |
| SCHEMBL3838345 | 0.81 | TGM2 (0.67) | NFE2L2CYP19A1FBP1VCPRAB9A | |
| SCHEMBL3838344 | 0.81 | TGM2 (0.67) | NFE2L2CYP19A1FBP1VCPRAB9A | |
| SCHEMBL11752570 | 0.80 | CYP19A1 (0.78) | NFE2L2CYP19A1FBP1VCPRAB9A | |
| SCHEMBL11752577 | 0.80 | CYP19A1 (0.78) | NFE2L2CYP19A1FBP1VCPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874845-B1 | PYRIDO (2,3-B) PYRAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6117875-A | Pyrido (2,3-B) pyrazine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-0874845-A1 | PYRIDO (2,3-B) PYRAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024355-A1 | PYRIDO (2,3-B) PYRAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |