Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 17/20 | 0.55 |
| ▸ | METAP1 | P53582 | 8/20 | 0.49 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7358094 | 0.99 | METAP2 (0.54) | METAP2METAP1REN | |
| SCHEMBL7353359 | 0.80 | METAP2 (0.78) | METAP2METAP1REN | |
| Hydrochloric Acid SCHEMBL7356007 | 0.79 | METAP2 (0.76) | METAP2METAP1REN | |
| SCHEMBL6477548 | 0.79 | METAP2 (0.61) | METAP2METAP1REN | |
| SCHEMBL6477201 | 0.78 | METAP2 (0.56) | METAP2METAP1REN | |
| SCHEMBL7357663 | 0.77 | METAP2 (0.56) | METAP2METAP1REN | |
| Hydrochloric Acid SCHEMBL7358994 | 0.76 | METAP2 (0.55) | METAP2METAP1REN | |
| SCHEMBL6475764 | 0.76 | METAP2 (0.60) | METAP2METAP1REN | |
| SCHEMBL7341595 | 0.76 | METAP2 (0.60) | METAP2METAP1REN | |
| SCHEMBL7355544 | 0.76 | METAP2 (0.58) | METAP2METAP1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242494-B1 | ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES | 2001-06-05 | — | — | US | claimed |