Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 16/20 | 0.56 |
| ▸ | METAP1 | P53582 | 8/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7358994 | 0.99 | METAP2 (0.55) | METAP2METAP1EPHX1RENCPB2 | |
| SCHEMBL6477201 | 0.79 | METAP2 (0.56) | METAP2METAP1REN | |
| SCHEMBL7358549 | 0.78 | METAP2 (0.54) | METAP2METAP1 | |
| SCHEMBL9514512 | 0.78 | METAP2 (0.62) | METAP2METAP1REN | |
| SCHEMBL9514498 | 0.78 | METAP2 (0.62) | METAP2METAP1REN | |
| SCHEMBL9514503 | 0.78 | METAP2 (0.62) | METAP2METAP1REN | |
| Hydrochloric Acid SCHEMBL7353863 | 0.78 | METAP2 (0.53) | METAP2METAP1 | |
| SCHEMBL7361727 | 0.77 | METAP2 (0.55) | METAP2METAP1REN | |
| SCHEMBL6475764 | 0.77 | METAP2 (0.60) | METAP2METAP1REN | |
| SCHEMBL7341595 | 0.77 | METAP2 (0.60) | METAP2METAP1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242494-B1 | ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES | 2001-06-05 | — | — | US | claimed |
| US-6242494-B1 | ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES | 2001-06-05 | — | — | US | disclosed |