Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361869 | 1.00 | FKBP1A (0.48) | FKBP1AALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL17893034 | 0.82 | FKBP1A (0.51) | FKBP1AALDH1A1 | |
| SCHEMBL17896181 | 0.82 | FKBP1A (0.51) | FKBP1AALDH1A1 | |
| SCHEMBL8332542 | 0.82 | FKBP1A (0.51) | FKBP1AALDH1A1 | |
| SCHEMBL7423869 | 0.81 | POLB (0.51) | FKBP1AALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL7802196 | 0.80 | POLB (0.52) | FKBP1AALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL2300448 | 0.80 | POLB (0.52) | FKBP1AALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL1864842 | 0.80 | POLB (0.52) | FKBP1AALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL11264038 | 0.79 | FKBP1A (0.53) | FKBP1AALDH1A1 | |
| SCHEMBL16857515 | 0.79 | POLB (0.52) | FKBP1APSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014706-A1 | CYCLOPENTANE-DERIVED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | PFIZER LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |