Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | MME | P08473 | 2/20 | 0.54 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367809 | 0.88 | ACE (0.70) | ACEMMEMMEL1ECE1 | |
| SCHEMBL7367811 | 0.88 | ACE (0.70) | ACEMMEMMEL1ECE1 | |
| SCHEMBL7318461 | 0.88 | ACE (0.70) | ACEMMEMMEL1ECE1 | |
| SCHEMBL7367705 | 0.87 | ACE (0.54) | ACEMMEMMEL1ECE1 | |
| SCHEMBL10791111 | 0.86 | ACE (0.68) | ACEMMEMMEL1ECE1 | |
| SCHEMBL10789074 | 0.86 | ACE (0.68) | ACEMMEMMEL1ECE1 | |
| SCHEMBL7368519 | 0.86 | MMEL1 (0.74) | ACEMMEMMEL1 | |
| SCHEMBL7371290 | 0.86 | MMEL1 (0.74) | ACEMMEMMEL1 | |
| SCHEMBL7371286 | 0.86 | MMEL1 (0.74) | ACEMMEMMEL1 | |
| SCHEMBL7398127 | 0.84 | MME (0.51) | ACEMMEMMEL1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |