SCHEMBL4839280

SCHEMBL4839280

CCC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
FABP5 Q01469 3/20 0.51
FABP7 O15540 2/20 0.51
EPHX2 P34913 1/20 0.49
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CYP1A2 P05177 1/20 0.46
CASP3 P42574 1/20 0.43
POLB P06746 1/20 0.43
HTR2A P28223 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29779340 0.87 KMT2A (0.50) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL30781736 0.87 KMT2A (0.50) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL47693 0.87 KMT2A (0.50) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL5497604 0.86 KMT2A (0.55) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL846010 0.84 KMT2A (0.54) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL10071038 0.84 KMT2A (0.50) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL20820035 0.84 KMT2A (0.58) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL30977665 0.84 KMT2A (0.58) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL3888794 0.83 KMT2A (0.54) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL14612149 0.83 KMT2A (0.52) KMT2AFABP5FABP7EPHX2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037405-B2 Anti-CD70 antibody drug conjugates AMBRX, INC. 2024-07-16 US disclosed
US-12030834-B2 Methods of synthesizing 4-valyloxybutyric acid XWPharma Ltd. (KY) 2024-07-09 US disclosed
US-20240067674-A1 METHOD FOR LOADING AMINO ACID ON RESIN FOR SOLID-PHASE SYNTHESIS CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-02-29 US disclosed
US-20240018208-A1 CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS JANSSEN PHARMACEUTICA NV (BE) 2024-01-18 US disclosed
US-20230399361-A1 MACROCYCLIC PEPTIDES UNIVERSITY OF NOTRE DAME DU LAC 2023-12-14 US disclosed
US-20230365542-A1 Selective Agonists of 5-HT2A Receptor and Methods of Use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-11-16 US disclosed
US-20230357130-A1 METHODS OF SYNTHESIZING 4-VALYLOXYBUTYRIC ACID XWPharma Ltd. (KY) 2023-11-09 US disclosed
US-11779646-B2 Dynamic user-programmable materials including stimuli-responsive proteins UNIVERSITY OF WASHINGTON (US) 2023-10-10 US disclosed
US-11780842-B2 TYK2 pseudokinase ligands VENTYX BIOSCIENCES, INC. (US) 2023-10-10 US disclosed
US-20230295320-A1 Anti-CD70 Antibody Drug Conjugates AMBRX, INC. (US) 2023-09-21 US disclosed
US-20080300287-A1 Peptidic Compounds UNIVERSITY OF WOLLONGONG (AU) 2008-12-04 US disclosed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US disclosed
US-7338805-B2 Labeling reagents, methods for synthesizing such reagents and methods for detecting biological molecules BIO MERIEUX (FR) 2008-03-04 US disclosed
US-20080009026-A1 FLUOROGENIC PROTEIN KINASE SUBSTRATES INVITROGEN CORPORATION (US) 2008-01-10 US disclosed
US-7312306-B2 Substituted heterocyclic acyl-tripeptides useful as thrombin receptor modulators ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2007-12-25 US disclosed
US-20070196860-A1 Methods for Measuring Real Time Kinase Activity INVITROGEN CORPORATION (US) 2007-08-23 US disclosed
US-7256253-B2 Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components CONJUCHEM BIOTECHNOLOGIES INC. (CA) 2007-08-14 US disclosed
US-20070154882-A1 Beta-polypeptides that inhibit cytomegalovirus infection NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-07-05 US disclosed
EP-1518862-B1 Solid phase native chemical ligation of unprotected or n-terminal cysteine protected peptides in aqueous solution GRYPHON THERAPEUTICS INC (US) 2007-02-21 EP disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037405-B2 Anti-CD70 antibody drug conjugates CD74, CD63, CD47 KMT2A 2012/4885FABP5 2241/4885FABP7 2593/4885
US-20230365542-A1 Selective Agonists of 5-HT2A Receptor and Methods of Use HTR2A, HTR2C, HTR2B KMT2A 1435/4885FABP5 910/4885FABP7 215/4885
US-11779646-B2 Dynamic user-programmable materials including stimuli-responsive proteins MSN, SUMO2, PEBP1 KMT2A 1779/4885FABP5 407/4885FABP7 613/4885
US-11780842-B2 TYK2 pseudokinase ligands TYK2, JAK2, PTK2B KMT2A 901/4885FABP5 4217/4885FABP7 4210/4885
US-20080300287-A1 Peptidic Compounds VIP, NGLY1, FURIN KMT2A 4643/4885FABP5 1385/4885FABP7 3170/4885
US-20240067674-A1 METHOD FOR LOADING AMINO ACID ON RESIN FOR SOLID-PHASE SYNTHESIS SLC7A5, SLC7A1, MAX KMT2A 2228/4885FABP5 1822/4885FABP7 2364/4885
US-12030834-B2 Methods of synthesizing 4-valyloxybutyric acid GABBR1, GABBR2, GABRB3 KMT2A 2039/4885FABP5 464/4885FABP7 479/4885
US-20240018208-A1 CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS NPY4R, NPY5R, NPY1R KMT2A 2517/4885FABP5 639/4885FABP7 867/4885
US-20230357130-A1 METHODS OF SYNTHESIZING 4-VALYLOXYBUTYRIC ACID GABBR1, GABBR2, GABRB3 KMT2A 2039/4885FABP5 464/4885FABP7 479/4885
US-20070196860-A1 Methods for Measuring Real Time Kinase Activity MAP4K5, MAP3K9, MAP4K2 KMT2A 1798/4885FABP5 1616/4885FABP7 1181/4885
US-20230295320-A1 Anti-CD70 Antibody Drug Conjugates CD63, CD74, CD99 KMT2A 1890/4885FABP5 2184/4885FABP7 2416/4885
US-20230399361-A1 MACROCYCLIC PEPTIDES APP, MAPT, NEFM KMT2A 2854/4885FABP5 3385/4885FABP7 262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.