Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.42 |
| ▸ | CA2 | P00918 | 13/20 | 0.42 |
| ▸ | CA9 | Q16790 | 11/20 | 0.42 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1650430 | 0.74 | TSHR (0.33) | HSD17B10 | |
| SCHEMBL8287 | 0.72 | DAO (0.32) | — | |
| SCHEMBL6542433 | 0.70 | DAO (0.31) | — | |
| SCHEMBL30218272 | 0.70 | GAA (0.35) | CA1CA2CA9 | |
| SCHEMBL653804 | 0.67 | CA1 (0.57) | CA1CA2CA9CA5ACA6 | |
| SCHEMBL10854249 | 0.67 | CA2 (0.58) | CA1CA2CA9CA5ACA6 | |
| SCHEMBL7974789 | 0.67 | BCHE (0.39) | CA1CA2CA9CA12CA7 | |
| SCHEMBL7362125 | 0.67 | PTGS2 (0.44) | CA2 | |
| SCHEMBL7984058 | 0.66 | TSHR (0.38) | CA1CA2CA9CYP2C9CA12 | |
| SCHEMBL27470518 | 0.64 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026195-A1 | BENZOTHIAZINE DIOXIDES AS ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-08-29 | — | — | WO | disclosed |