Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.58 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.58 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.58 |
| ▸ | BCL9 | O00512 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358681 | 0.86 | KMT2A (0.62) | KMT2APTPN7PTPN12PTPN22BCL9 | |
| SCHEMBL7357774 | 0.86 | KMT2A (0.62) | KMT2APTPN7PTPN12PTPN22BCL9 | |
| SCHEMBL7359954 | 0.83 | PTPN7 (0.74) | KMT2APTPN7PTPN12PTPN22BCL9 | |
| SCHEMBL7361663 | 0.83 | PTPN7 (0.60) | KMT2APTPN7PTPN12PTPN22BCL9 | |
| SCHEMBL7357629 | 0.82 | KMT2A (0.62) | KMT2APTPN7PTPN12PTPN22BCL9 | |
| SCHEMBL27542011 | 0.81 | PTPN7 (0.67) | KMT2APTPN7PTPN12PTPN22BCL9 | |
| SCHEMBL11605368 | 0.80 | PTPN7 (0.69) | KMT2APTPN7PTPN12PTPN22BCL9 | |
| SCHEMBL28653268 | 0.78 | HSPB1 (0.53) | KMT2ABCL9CTNNB1ALDH1A1MAPT | |
| SCHEMBL8832170 | 0.77 | BCL9 (0.65) | KMT2APTPN7PTPN12PTPN22BCL9 | |
| SCHEMBL8832017 | 0.77 | GAA (0.66) | KMT2APTPN7PTPN12PTPN22BCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413750-A1 | RENIN INHIBITORY PEPTIDES CONTAINING A SUBSTITUTED PHENOXYACETYLE GROUP | THE UPJOHN COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| WO-1989010920-A1 | RENIN INHIBITORY PEPTIDES CONTAINING A SUBSTITUTED PHENOXYACETYLE GROUP | THE UPJOHN COMPANY (US) | 1989-11-16 | — | — | WO | disclosed |