Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.61 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.61 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | BCL9 | O00512 | 1/20 | 0.60 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605368 | 0.92 | PTPN7 (0.69) | GAALMNAPTGS2PTPN7PTPN12 | |
| SCHEMBL27542011 | 0.87 | PTPN7 (0.67) | LMNAPTGS2PTPN7PTPN12PTPN22 | |
| SCHEMBL8832170 | 0.86 | BCL9 (0.65) | LMNAPTGS2PTPN7PTPN12PTPN22 | |
| SCHEMBL839776 | 0.84 | PTGS2 (0.83) | PTGS2KMT2AALDH1A1MEN1POLB | |
| SCHEMBL10311842 | 0.84 | BCL9 (0.67) | GAALMNAPTGS2PTPN7PTPN12 | |
| SCHEMBL8832283 | 0.83 | BCL9 (0.62) | LMNAPTGS2PTPN7PTPN12PTPN22 | |
| SCHEMBL7358681 | 0.83 | KMT2A (0.62) | GAALMNAPTGS2PTPN7PTPN12 | |
| SCHEMBL26083579 | 0.82 | MEN1 (0.64) | GAALMNAPTGS2KMT2AALDH1A1 | |
| SCHEMBL9363100 | 0.82 | PTPN7 (0.64) | PTGS2PTPN7PTPN12PTPN22KMT2A | |
| SCHEMBL8832495 | 0.82 | PTPN7 (0.57) | LMNAPTGS2PTPN7PTPN12PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670492-A | BACTERICIDE, ANTITUMOR AGENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0702014-A1 | DC-89 DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-03-20 | — | — | EP | disclosed |
| EP-0354583-B1 | DC-88A derivatives | KYOWA HAKKO KOGYO KK (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5248692-A | DC-89 derivatives as anti-tumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-28 | — | — | US | disclosed |
| US-5214065-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| US-5117006-A | DC-88A DERIVATIVES USEFUL AS ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| US-5084468-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0461603-A1 | DC-89 derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |
| EP-0354583-A1 | DC-88A derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |