Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 1/20 | 0.56 |
| ▸ | ME1 | P48163 | 1/20 | 0.56 |
| ▸ | ME3 | Q16798 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.54 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.54 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473519 | 0.95 | MAPT (0.54) | ME2ME1ME3MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7362069 | 0.86 | TPSAB1 (0.53) | ME2ME1ME3MAPTALDH1A1 | |
| SCHEMBL12814351 | 0.85 | ITGB3 (0.62) | ME2ME1ME3MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL8477696 | 0.84 | ITGB3 (0.56) | ME2ME1ME3MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7369072 | 0.82 | TPSAB1 (0.53) | ME2ME1ME3MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7358202 | 0.81 | MAPK1 (0.51) | ME2ME1ME3MAPTTPSAB1 | |
| SCHEMBL8325106 | 0.79 | ITGB3 (0.55) | ME2ME1ME3ALDH1A1TPSAB1 | |
| SCHEMBL8662762 | 0.78 | ITGB3 (0.54) | MAPTALDH1A1TPSAB1TPSD1TPSG1 | |
| SCHEMBL8662766 | 0.78 | ITGB3 (0.54) | MAPTALDH1A1TPSAB1TPSD1TPSG1 | |
| SCHEMBL5533561 | 0.77 | ITGB3 (0.63) | ME2ME1ME3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |