Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 6/20 | 0.69 |
| ▸ | HTR3A | P46098 | 2/20 | 0.69 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.69 |
| ▸ | HTR3B | O95264 | 1/20 | 0.69 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.69 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7359459 | 0.99 | HTR4 (0.68) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL7355049 | 0.98 | HTR4 (0.67) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL7361680 | 0.92 | HTR4 (0.65) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7432070 | 0.88 | HTR4 (0.64) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7430663 | 0.82 | HTR4 (1.00) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL7365194 | 0.81 | HTR4 (0.51) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7355300 | 0.81 | HTR4 (0.55) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL7361117 | 0.80 | HTR4 (0.54) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7365594 | 0.79 | HTR4 (0.60) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL14810412 | 0.79 | HTR4 (0.59) | HTR4HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996033186-A1 | SUBSTITUTED DIHYDROBENZOFURAN DERIVATIVES AS 5-HT4 AGONISTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1996-10-24 | — | — | WO | claimed |
| WO-1996033186-A1 | SUBSTITUTED DIHYDROBENZOFURAN DERIVATIVES AS 5-HT4 AGONISTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1996-10-24 | — | — | WO | disclosed |