Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 8/20 | 0.60 |
| ▸ | HTR3A | P46098 | 5/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.51 |
| ▸ | HTR3B | O95264 | 2/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7363349 | 0.99 | HTR4 (0.59) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL7355300 | 0.94 | HTR4 (0.55) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| Hydrochloric Acid SCHEMBL7361117 | 0.93 | HTR4 (0.54) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| Hydrochloric Acid SCHEMBL7361288 | 0.82 | HTR4 (0.47) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| Hydrochloric Acid SCHEMBL7361680 | 0.80 | HTR4 (0.65) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL27360404 | 0.79 | HTR4 (0.50) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL7362282 | 0.79 | HTR4 (0.69) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| Hydrochloric Acid SCHEMBL7365194 | 0.79 | HTR4 (0.51) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL7360905 | 0.79 | HTR4 (0.81) | HTR4HTR3AADRA2CADRA1AHTR1A | |
| SCHEMBL8498108 | 0.79 | HTR4 (0.75) | HTR4HTR3AADRA2CADRA1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996033186-A1 | SUBSTITUTED DIHYDROBENZOFURAN DERIVATIVES AS 5-HT4 AGONISTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1996-10-24 | — | — | WO | disclosed |