Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357492 | 0.91 | FFAR1 (0.47) | FFAR1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7363865 | 0.86 | KCNH2 (0.47) | FFAR1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7368439 | 0.85 | PDCD1 (0.40) | FFAR1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7363749 | 0.82 | F2 (0.59) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL8348245 | 0.80 | FFAR1 (0.42) | FFAR1FFAR4MAOBMEP1AMEP1B | |
| SCHEMBL7362467 | 0.80 | FFAR1 (0.53) | FFAR1FFAR4MEN1USP2KMT2A | |
| Trifluoroacetic Acid SCHEMBL7362302 | 0.79 | F2 (0.57) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7363751 | 0.79 | F2 (0.42) | F2PRSS1PRSS2PRSS3MAOB | |
| SCHEMBL7362306 | 0.78 | F2 (0.45) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL7450712 | 0.78 | F2 (0.67) | F2PRSS1PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892780-B1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |